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Dear Ladies and Gentlemen,
Over the past few weeks, we have already provided you with extensive insights into the topics of the HOF TECH-Innovation-Day 2025.
Now the time has come:
On November 12, we will officially open our doors in Marburg –
and cordially invite you to be part of it.
A full day of practice, knowledge, and inspiration dedicated to the three core topics of the TECH-Innovation-Day.
Venue: Welcome Hotel Marburg, Pilgrimstein 29, 35037 Marburg
Date: 12 November 2025 from 8:30 a.m. to approx. 2:30 p.m.
Registration deadline: November 7, 2025
Get-together on the evening before: November 11, from 6:30 p.m. at the hotel bar “Pinte”
Look forward to in-depth expert presentations, exciting case studies from the industry, and forward-looking technologies for pharmaceutical production.
A compact program that informs and inspires – in a relaxed atmosphere.
Program – HOF Tech-Innovation Day
08:00–08:30 Uhr
Arrival and registration
08:30–08:45 a.m.
Welcome & Introduction
Dr. A. Hof
08:45–09:45 a.m.
Annex 1-Compliant Loading and Unloading Systems
J. Dietermann & P. Schneider
09:45–10:15 a.m.
Coffee Break
Networking
10:15–12:15 p.m.
Sustainable Cooling Technologies / Processes
T. Frank, F. Plaum, D. Walbrecht, Roche
12:15–13:15 p.m.
Lunch
Networking
13:15–14:30 p.m.
Process Analytics for Freeze Dryers
J. Kuhl, E. Baldauf
from 14:30 p.m.
Factory Tour & Networking Get-together
Here’s what to expect during the event:
Sustainable Cooling Technologies and Processes
The demand for energy-efficient and environmentally friendly cooling technologies continues to rise – especially in sensitive applications such as freeze drying and freeze-thaw processes. At the HOF TECH-Innovation-Day, we will explore current developments, regulatory frameworks, and practical solutions for a sustainable future in cooling technology for pharmaceutical applications. In three exciting sessions, you will gain a comprehensive overview of new regulations, technical innovations, and successful industrial best practices.
Session 1:
F-Gas Regulation – Impacts and Opportunities
Insights into current and upcoming EU F-Gas Regulation and REACH legislation. Which refrigerants will remain approved in the future? What transition periods and obligations apply to operators? Learn more about the background of these regulations and how to avoid compliance risks.
Thomas Frank
(Managing Director)
Refolution Industriekälte GmbH
Session 2:
Alternative Cooling Technologies
This session focuses on innovative and sustainable cooling concepts designed to make processes future-proof and independent of regulatory restrictions.
In addition to the technologies themselves, practical implementations will be presented – including examples from HOF freeze-drying systems and HOF freeze-thaw solutions.
Fabian Plaum
(Sales Management)
Session 3:
Case Study – Sustainable Freeze Drying in Practice
Gain deep insights into the real-world implementation of sustainable cooling technologies in industrial freeze drying. An industry user will share the entire journey – from planning and selecting suitable systems to on-site commissioning. Challenges such as process stability, energy efficiency, investment costs, and maintenance will also be addressed.
Roche Diagnostics GmbH
Look forward to practical insights:
Experience the future of sustainable cooling technology – from regulatory frameworks and alternative systems to proven industry applications.
Discover how innovative technologies using natural refrigerants, energy-efficient processes, and intelligent system solutions form the foundation for a climate-friendly and economically viable production.
Tomorrow starts today
“Sustainable cooling technologies are not a trend, but the logical consequence of responsible plant engineering.”
Fabian Plaum
(Sales Management)
Factory Tour & Networking
Experience HOF live – with an exclusive guided tour of our facilities in Lohra and Mornshausen.
On November 11 and 12, from 3:00 to 5:00 p.m.
Application of Process Analytical Tools in Freeze-Drying – Transparency in the Process
How can product quality in pharmaceutical freeze-drying be monitored even more precisely in the future?
How can product quality in pharmaceutical freeze-drying be monitored even more precisely in the future?
Mass spectrometry opens up new insights – directly into the process.
But how can this technology be efficiently integrated into existing systems without fundamentally changing the production environment?
Especially in validated production lines, the challenge is to combine stability and innovation.
Modern analytics should not only measure – but understand.
At the HOF TECH-Innovation-Day 2025, we will demonstrate how inline-capable mass spectrometry makes the freeze-drying process more transparent, safer, and more efficient – from development scale to large-scale production.
Gain practical insights into the use of modern process analytical tools, discover real-world applications, and take away valuable impulses for further enhancing process reliability in freeze-drying.
We will show the latest trends in loading and unloading systems, including robot-assisted loading and unloading of freeze dryers with HOF SIRIUS, and give you an exclusive preview of a new HOF product family that will set new standards.
Johannes Kuhl
Certified Engineer
Sales Management
Emanuel Baldauf
Dr.-Ing., Head of Process Engineering Systems
Vetter Pharma-Fertigung GmbH & Co. KG
Look forward to fascinating insights:
A presentation on the use of modern, inline-capable mass spectrometry – including an overview of the technological fundamentals, system integration, and a practice-oriented case study.
Tomorrow starts today.
“Modern process analytics brings clarity to the details –
making freeze-drying more precise and traceable.”
Johannes Kuhl
Certified Engineer
Sales Management
Annex 1 – Requirements and Implementation
How can the new Annex 1 requirements be put into practice?
The new Annex 1 is already in force –
but many questions remain:
How can existing production lines be upgraded to meet the new requirements without having to replace freeze dryers or filling machines?
Especially established systems are expected to further produce in a reliable way, while a complete reinvestment means enormous time and cost efforts. So, what are the solutions to remain compliant with Annex 1?
That’s exactly what we will demonstrate at the
HOF TECH-Innovation-Day 2025.
And when planning new lines – whether small scale or large-scale production – the rule is: think of tomorrow today.
We will show the latest trends in loading and unloading systems, including robot-assisted loading and unloading of freeze dryers with HOF SIRIUS, and give you an exclusive preview of a new HOF product family that will set new standards.
Peter Schneider
(Sales Management)
Julien Dietermann
(Sales Management)
You may also look forward to:
join us for a presentation on Annex 1 compliant loading and unloading systems – including an overview of the regulatory requirements and their technical implementation at HOF – as well as a practical case study.
#SIRIUS #GENEX #Robotics –
Tomorrow starts today.
“Annex 1 brings clear requirements. Our task is to provide customers with future-proof loading and unloading systems that can be seamlessly integrated into both existing and new lines.”
Peter Schneider
(Sales Management)
We look forward to welcoming you!
Registration
Organizational Notes:
The event will primarily be held in German. Simultaneous English translation is available upon request.
A room block is available for individual booking at the Welcome Hotel Marburg.
Please make your reservation directly with the hotel using the keyword "HOF TECH-Innovation-Day":
Tel.: +49 6421 918-0
info.mar(at)welcome-hotels.com
Stay tuned – more details about the event will follow soon.
Best regards,
Your HOF Team