HOF CryoBlizzard - a technology sets new standards

As an innovative market leader, HOF always puts emphasis on customer needs and market demands. Together with Mirai Intex (https://mirai-intex.com/de/startseite/) as a partner, the HOF CryoBlizzard has been developed as a new technology for our market segment.

A HOF freeze dryer from 1998 was retrofitted especially for this R&D project. The plant is a freeze dryer with a batch capacity of 40 kg for insulin production. Before this retrofit, refrigeration was achieved by two refrigeration sets, each containing 12 kg of the refrigerant R404A (GWP₁₀₀ = 3922). The process plant was controlled by a Siemens S5 control system.
 

Great performance with homogeneous temperature distribution

The overall retrofit has upgraded the lyo to a new refrigeration process, the HOF CryoBlizzard and to the current S7-1500 control system. With this new process, the refrigeration system consists of redundant cold air machines which are connected to a central primary tank in a modular system. The primary tank supplies the consuming units, such as shelf stack, ice condenser or blast freezer directly with the refrigerant medium and can therefore provide large capacities with homogeneous temperature distribution, all within a very short time. The usage of such a primary tank results in the fact that the consumption of cooling water and the power remain constant and no load peaks occur during the supply. Additionally, the cooling water consumption was reduced by half.
 

Air as refrigerant is free of charge and always available

The cold air machines from Mirai Intex are chillers which operate with air as a refrigerant using the Brayton cycle process. The maximum overpressure in the machines is 3 bar(a) and can be compared to that in a bicycle tire. This makes these machines particularly safe and environmentally friendly. Furthermore, no special requirements result in regards to the machine room set-up, employee training and recurrent testing. And in addition to all this, air as a refrigerant is free of charge and always available, has a GWP₁₀₀ value of 0 (zero) and is therefore not affected by any regulations.

“As an innovative equipment manufacturer, we knew thatwe have to come up with a new way forward - for our customers. The advantages of air as a refrigerant are obvious. Air is available, non-flammable, non-toxic and poses no risk of suffocation. Air has no GWP value and is therefore not subject to the F-Gas Regulation or any other directives. That is the future!”, says Oliver Fleischer from the refrigeration engineering and service management department at HOF.
 

The HOF CryoBlizzard turbocompressor, oil-free and almost wear-free

The refrigeration circuit is driven by an air-bearing supported, oil-free turbo compressor–expander unit that runs with up to 88000 rpm and virtually no wear. The refrigeration medium is cooled in a heat transfer unit, integrated into the chiller. The air that is heated this way, is aspirated by the turbocharger and compressed (steps 1 to 2). Subsequently, the energy in the gas chiller is dissipated to the environment and cooled down (steps 2 to 3). In an inner heat transfer unit, the recuperator, the air is strongly cooled down (steps 3 to 4) and then relaxed for effective use in the expander (steps 4 to 5). This work is returned to compression. The energy is now absorbed through heating of the air in the cold medium/heat transfer unit (steps 5 to 6). After the air in the recuperator has been heated again (steps 6 to 1), it is aspirated by the compressor and the cycle starts anew.
 

With HOF CryoBlizzard - renewing existing systems as a retrofit or implementing new systems

The modular design enables the capacity of the HOF CryoBlizzard to be scaled up or down as needed. This allos its adaption from small freeze dryer units all the way to a central cooling system for complete factories. Existing plants can be retrofitted and new plants can be implemented. With the HOF CryoBlizzard, HOF has developed a future-proof solution for freeze drying and blast freezing which is not only safe for employees and the environment, but also sets new standards with regard to the quality and availability of the application. Therefore, the HOF CryoBlizzard is another alternative technology by HOF to solve the GWP-issue of synthetic refrigerants in the long-run.

In cooperation with the project partners:

MIRAI INTEX GmbH
www.mirai-intex.com/de/startseite

Refolution Industriekälte GmbH
www.refolution.de

We are especially happy, that the technological magazine „DIE KÄLTE + Klimatechnik“ has published an article about our technology already in its most current issue. Source: Alfons W. Gentner Verlag GmbH & Co. KG, Fachmagazin „DIE KÄLTE + Klimatechnik“, Article "Natürlich am besten", issue 01.2020, pages 18 - 19.
 

For more information on the innovative development, please contact Mr. Oliver Fleischer (Phone: 0049 6462-9169-228 - Email: oliver.fleischer(at)hof-sonderanlagen.de) or any other HOF representative.

Dear Sir/Madam

Despite some new coronavirus hotspots, Germany and Europe overall are on a good track to work themselves out of this crisis. Nevertheless, we all have to stay highly alert.

In this regard, HOF continues to diligently do its homework in order to maintain the hygiene standards among employees. We would like to once again say thank you to our employees for their commitment!
 

Looking ahead

Despite the pandemic, we are deliberately directing our attention to the future:
whether with the announcement for the Specialist Forum 2020 this November or with our many specialists who use their great know-how and many new innovative ideas to continuously develop our capacities for our customers.
This is also reflected in the fact that HOF received the TOP 100 Innovator award for the fifth time running!

To the video >
 

Necessity is the mother of invention

Ranga Yogeshwar, science journalist and longstanding mentor of the TOP 100: “The coronavirus has had an immense impact on our world. It is a crisis, but we all know the saying that ‘necessity is the mother of invention’. And innovators in particular sometimes find opportunities in a crisis. The TOP 100 is about innovators, about showing how these companies have the courage to reinvent themselves, to develop new things and to thereby become a shining example for others.”
 

TOP 100 panel member Dorothee Bär

Minister of state at the German Chancellery

“Innovative medium-sized companies are the driving force of the successful ‘Made in Germany’ concept, and TOP 100 helps to make those companies visible who use their power of innovation to contribute to Germany’s economic success and see digitalisation as an opportunity.”
 

Award for the most innovative medium-sized German companies

The TOP 100 – the most innovative medium-sized German companies – were selected for the 27th time this year. HOF had to take part in a sophisticated scientific selection process. The focus is on innovation management and innovation success.

The system, which was developed by Prof. Dr Nikolaus Franke, gives equal opportunities to manufacturing companies and service providers while also taking into account the respective size of the enterprises. In this independent selection process, HOF and its around 270 employees stood out in particular on account of its innovation success.
Prof. Dr Nikolaus Franke, Scientific Director of the TOP 100: “HOF Sonderanlagenbau GmbH is consistently and fully focused on innovation. This becomes particularly evident in the external orientation, which is the way that open innovation is put into practice.”
 

Digital award

Due to the coronavirus epidemic, the awards were handed out over video this year. One of the presenters was Linda Zervakis, a German newsreader. “I would have loved to do this again in person, but it had to be digital this time.” Ranga Yogeshwar: “This is the fifth time I can say ‘Congratulations!’ to HOF Sonderanlagenbau GmbH for winning the TOP 100 award. Brilliant!”
 

HOF says thank you

“We are very pleased to be among the winners for the fifth time and would like to thank all employees for their motivation and power of innovation and of course we also thank our customers for the regular exchange of knowledge.”

Sincerely

Hans-Georg Hof and Dr Alexander Hof

Bildquelle: www.TOP100.de

Sigraph announcement:

The CAE system SIGRAPH, used to create circuit diagrams until 2004, has already been discontinued by the manufacturer for some time. Economic processing of the circuit diagrams is therefore unfortunately no longer possible. We can therefore process changes in SIGRAPH diagrams only to a limited extent and must discontinue support for these circuit diagrams from 2022.

For larger modifications, we recommend converting the circuit diagrams to EPLAN P8.

EPLAN 5 announcements:

The CAE system EPLAN 5, used to create circuit diagrams between 2004 and 2016, has been replaced by the EPLAN P8 system. As of version EPLAN P8/2.8, EPLAN 5 can no longer run in a system environment. Furthermore, operation under Windows 10 is not released.
In the future, EPLAN 5 projects must therefore be migrated to P8 to enable further processing.

Bernd Becker (Head of Electronics Engineering)

"If modifications to your affected systems are planned, we will be happy to support you with a future-oriented solution."

HOF among TOP 100 companies again

398 companies entered the current round for a TOP 100 award.
TOP 100 uses a scientific system to evaluate the innovation management of SMEs.
This system, which was developed by Prof. Dr Nikolaus Franke, gives equal chances to manufacturing companies and service providers while also taking into account the respective size of the enterprises.
In this independent selection process, HOF and its 265 employees stood out in particular on account of its innovation success.

Finding innovative solutions – exploring new directions

For 30 years, the TOP 100 company has been specialised in the development and manufacturing of freeze drying systems, loading and unloading systems, and freezing and thawing equipment for the pharmaceutical industry. More than 2,000 systems in 27 countries prove the worldwide success of HOF.
Where bottles filled with frozen blood plasma used to be opened by people wearing gloves, this is now the task of a machine from the top innovator. The bottles are partially defrosted in an automatic process, opened with a so-called guillotine and then removed by robots for further processing of the plasma. The new innovative process from HOF is significantly faster and the system can operate around the clock.

“Being open to new things is a sign of a good innovation culture”

Physicist and scientific journalist Ranga Yogeshwar, who has been mentoring the competition since 2011, summarises the qualities of the TOP 100 as follows: “Being open to new things, tolerating mistakes, constantly striving to do things in a new and different way – those are the characteristics of a good innovation culture. A culture that is practised in the SMEs which we award with the TOP 100. They are exceptional medium-sized companies where the spirit of innovation has become part of their DNA. They are far-sighted, active entrepreneurs who focus on innovation every single day.” More information at www.top100.de.

HOF says thank you

“Receiving the award for the fourth time running makes us particularly proud.
We do not take it for granted and we will continue our endeavours to offer our customers the best, most innovative solutions.
But most of all, we want to thank our employees, without whom this success would not be possible.”

Bildquelle: www.TOP100.de