LYOCOM 2018 is based on Siemens TIA Professional 15.1. In contrast to the LYOCOM III system, all system components (freeze drying plant, vial transfer system and visualisation) are integrated in one project, so that the customer only has to manage one software version for the HOF Package Unit.

LYOCOM 2018 is a software for all freeze drying systems in combination with the loading and unloading systems and includes extensive features. The system features easy, intuitive operation, compared with a user-friendly and visually appealing user interface.

LYOCOM 2018 has the following distinguishing features:

• Use of Siemens F-CPU 15xx
• Uniform look and feel for operation of GT and VTS
• Development of a dedicated HOF library as per GAMP 5. Safety through the implemented TIA portal version check and tested module documentation of standard modules
• Fine-grained display of operating equipment down to the basic function level
• Extended service information from display of switching cycles of the operating equipment and optional batch-based performance recording
• Minimising of qualification work by using uniform screens, standardised program modules and a uniform text basis. Only the correct connection to the periphery has to be checked. Visualisation, error message generation, etc. are standardised and no longer require checking
• Extended system diagnosis. Siemens ProDiag was integrated for this purpose. This now makes it possible to display control sequences and interlocks on the visualisation directly from the PLC program, to immediately initiate diagnostics in case of process errors. The control of the door safety was integrated into the GT on an F control, also in the framework of better diagnostic options. Additionally, the Siemens hardware diagnostics are visualised and a torque path of the axes can be recorded for the servo drives during the diagnosis. All system components which are actuated from the control are also visualised and, with the appropriate authorisation, can also be actuated directly or locked, e.g. for service work
• Redundancy in communication by establishing an MRP ring already in the basic version
• The HOF FVP software is used for recipe management and batch logging. This ensures consistency of the recipes, from laboratory applications to the production lines
• Vertical and horizontal data interfaces are executed via Ethernet, allowing flexible interfaces to be mapped. The LYOCOM 2018 system offers interfaces to higher-level systems, e.g. MES and Data Historian. Here, the link to its higher-level system can be implemented individually with an interface to the PU
• Use of a new touch panel with new keyboard for sterile rooms
• Improved parameter mapping of the VTS with display of all parameters on one screen
• Automatic setting of IPC samples using a robot

“We are pleased that we have already been able to successfully integrate the new system into several new plants.”
Patrick Schuhmacher (Head of Software Engineering)

Things started rolling on Christmas Day. The two Christmas Truckers from HOF, Alex Wagner and Alex Winter, were taken to Landshut, where the journey to Bosnia with around 20 tons of relief goods on board began at 6 am on December 26.
We were able to park our trucks on the premises of the THW [German Federal Agency for Technical Relief] in Landshut so we could start bright and early from there with the maximum driving time. First, we were joined by two more trucks that had been parked there and drove to the Grieserwiese area. Here, the convoys were assembled and supplied with food and drink to last us for a week. We introduced ourselves and were received like old friends. Then the 47 trucks drove through the mediaeval centre of Landshut, where we received a send-off with a church service and various speeches, including by German-Romanian musician Peter Maffay.
Thousands of people lined the streets and waved us off. The THW had blocked all the roads so we had unhindered access to the motorway – the atmosphere gave us all goosebumps. At the border between Germany and Austria, the convoy split off towards their destinations: Romania, Bulgaria, Ukraine, Albania and Bosnia. Our destination on the first day was Croatia, where we arrived around 9:30 pm after a 16-hour day. The next morning, we continued to the Bosnian border, where we stopped for the whole day and kept the local customs authorities busy with our relief goods.
Later that afternoon, we were able to continue the journey to Bosnia. Our destination was Tuzla in the east of Bosnia, close to the Serbian border. After a long search with our six trucks, we were warmly received at the local university and invited to dinner.

The next morning, we split up to distribute the Christmas parcels in five different locations: four schools and nurseries along the Serbian border and a women’s shelter with numerous children. Getting to the nurseries or schools was not always easy, as the mountain paths were often overgrown and had to be cleared with a chainsaw. Many hands helped us with unloading. People were overjoyed to receive the parcels, as they provided them with essential items for themselves and their families, even if only for a short while.
After another night in Tuzla, we unloaded two more trucks on the following day before setting out for Banja Luka. We drove 200 kilometres across the mountains on roads that reminded us of East Germany before the reunification.
Once we arrived in Banja Luka, the last two trucks were unloaded and we started our journey home.
Our convoy stayed together until we reached the Obere Tauernalm services in Austria, where we said goodbye after a lovely dinner together – some of the trucks had to go in a different direction from there. For us, the day ended at 1:30 am at the Chiemsee lake, where we were warmly received at the Schalchen Hof Hotel with a little late-night snack. The next day was New Year’s Eve, and after a generous breakfast we started on the last leg of our journey. Our Bosnia adventure finally came to an end at 6:30 pm on New Year’s Eve, and were happy to be reunited with our families.
We can say that this aid campaign by HOF was a great success all around. We saw that our parcels actually arrived where they were meant to go – to the poor, children and others in need. When you see how a small bar of chocolate or a colouring book can put a smile on a child’s face – which we did – then we think that is proof that our company did exactly the right thing.

Alexander Wagner & Alexander Winter

HOF now looks back on more than 30 years of company history.
Since its founding in 1988, HOF has continuously developed into a globally operating and innovative company in the manufacturing of individual freeze-drying plants, loading & unloading systems and freezing and thawing equipment.

Step by step and always focusing on the essentials, the company has positioned itself as a market-oriented company, and has been for more three decades now the leading specialist for individual solutions in the pharmaceutical and biotechnological industry, with more than 270 employees within the HOF group.

We sincerely thank you for 30 years HOF Sonderanlagenbau GmbH and would like to thank all business partners who have accompanied us on this way for the good and successful cooperation.

Special thanks go to our customers for their trust and longstanding loyalty, and above all to our employees for their engagement and work, without them, we could not share our success. Therefore we are proud and grateful for the work they do each day.

We look forward to what is still to come and to the next years with you.

Yours sincerely
The HOF family

"Detailed information about our company anniversary can be found in our latest issue of HOFinsight."
Dr. Alexander Hof (management)

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